What EVs are
Extracellular vesicles are membrane-bound particles released by living cells. They are far smaller than cells, but retain biological information connected to their origin.
Our Science
A living source of biological information
Extracellular vesicles are microscopic particles released by cells. They circulate in blood carrying molecular information connected to the cells and tissues around them.
Cells communicate through extracellular vesicles.
EVs are part of normal cellular activity. Their contents and surface features can reflect biological changes taking place within a tumor and its surrounding environment, creating a distinct source of information for cancer detection research.
What they carry
EVs can carry proteins, lipids, nucleic acids and other molecular material. These signals offer a way to study active cellular processes through a blood sample.
Why they may matter
Many liquid-biopsy approaches rely primarily on fragments of tumor-derived DNA in circulation. EVBiome is studying a different biological source that may remain informative when DNA shedding is limited.
EVBiome's approach
Studying EV-associated signals in blood
EVBiome isolates and analyzes biological signals associated with extracellular vesicles. The company's work is focused on translating those signals into a practical blood-based diagnostic approach.
The distinction
A different window into cancer biology
EV biology does not depend solely on the abundance of tumor-derived DNA in circulation. That difference is the foundation of EVBiome's work.