Technology
NBI
Extracellular vesicles (EVs) are membranous particles, abundantly released by the cells in the extracellular space and in the biological fluids. EVs contain nucleic acids, proteins and lipids and their molecular content mirrors the one of the cell of origin. They are therefore a valuable source of information and a faithful representation of the state of health of the releasing cells.
EVBiome is leveraging on AEVA Biotech’s proprietary EVs isolation technology to capture EVs from biological fluids in a rapid, reproducible, cost-effective and high-throughput way. The innovative method is called NBI (Nickel Based Isolation) and exploits beads functionalized with nickel cations to recover intact EVs, still carrying their original features and thus usable for molecular characterizations of their biological content.
An exclusive license and research collaboration agreement is made by and between AEVA Biotech (Trento, Italy) and EVBiome for the exclusive license of AEVA patent related to isolation and analysis of extracellular vesicles, furthermore, AEVA agrees to conduct additional research and development for EVBiome in the field of early disease diagnosis in Oncology as well as neurodegenerative conditions.